The new version of WordPress -- released today -- is a Node app.
And they have a Mac desktop app.
I've tried them both, and they're really nice, and it's still WordPress.
The product has the same familiar organization and structure.
At the same time I'm finishing my own Node-based blogging system. It's really cool that WordPress is running in the same environment. There may be some interesting integrations possible as a result.
But first I have to ship. :->